Phyto Nature e²

A person with clear skin touches their cheek while smiling slightly. The word “new” appears on a purple banner in the top left, with purple spheres nearby. The lower half of the image is filled with a solid purple color.

with next-gen exosomes
gives 6 years back*

with next-gen exosomes
gives 6 years back

*Results at 8 weeks, based on a reduction in visible signs of skin ageing in an independent clinical study with 32 subjects, 2 applications/day

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BOTANICAL BLEND

visibly brightens and smooths

Close-up view of bubbly, slightly frothy sourdough starter or yeast dough in a round container, showing an off-white, creamy surface with small bubbles and air pockets.

BIO-FERMENTED ACETYL GLUCOSAMINE

Provides antioxidant protection

Abstract image featuring blue and white spheres, DNA helix strands, and swirling yellow lines on a light background, evoking a scientific or molecular theme.

EXOSOMES

support skin’s regeneration

A close-up, digitally rendered image of spherical blue and purple molecules or cells floating in a translucent, glowing environment, suggesting a microscopic or scientific view.

ENZYMES

removes dead cells for radiant skin

A sleek, modern purple bottle of Dermalogica South Africa phyto nature e² regenerating daily exosome leave-on treatment with a pump dispenser and white text targets skin regeneration, reducing fine lines and wrinkles.

A purple bottle of Dermalogica South Africa phyto nature e² regenerating daily exosome leave-on treatment is shown, with text highlighting its benefits: accelerates skin regeneration, reduces fine lines and wrinkles, and smooths for a brighter look.

A woman with smooth, glowing skin touches her face and smiles. Text: 1 use of Dermalogica South Africa phyto nature e² regenerating daily exosome leave-on treatment makes skin look and act younger, visibly reducing fine lines and wrinkles. Clinical proof below.

A graphic titled “how to layer your skin care” shows six labeled steps: cleanse, exfoliate, Dermalogica South Africa phyto nature e² regenerating daily exosome leave-on treatment for skin regeneration, serum, moisturize, and SPF—each with a matching product outline.

R 3,499.00

In stock

Daily exosome leave-on visibly smooths and supports skin regeneration. Formulated with next-gen exosomes and enzymes, this lightweight, silky leave-on helps reawaken skin’s natural surface renewal process, improving natural regeneration by 86%.*

recommended for

mature or prematurely-aging skin
fine lines and wrinkles
Loss of firmness and elasticity

Quantity

see the results

visibly diminishes fine lines + wrinkles in 2 weeks*

Before

Baseline: Day 0, before using the Phyto Nature E² daily leave-on.

After

Results on day 14 of an 8 week independent clinical study with 32 subjects, 2 applications/day.

Frequently asked questions

Phyto Nature E² is a regenerating daily leave-on formulated for aging skin. It’s ideal for anyone seeking anti-aging skincare or a skin renewing treatment to address fine lines, wrinkles, dullness, and uneven texture. Recommended for mature or prematurely-aging skin, those experiencing fine lines, wrinkles, and loss of firmness. This leave-on exfoliant supports natural surface renewal for smoother, brighter, and more youthful-looking skin.
This anti-aging leave-on accelerates skin regeneration, visibly reduces fine lines and wrinkles, and resurfaces skin to improve brightness, texture, and smoothness. Daily exfoliating enzymes clear away dull surface cells, and regenerative exosomes act in multiple layers to diminish fine lines and wrinkles in as little as two weeks**. Improves natural skin regeneration by up to 86% versus untreated skin*.
Apply Phyto Nature E² to clean skin as the first step after cleansing. Allow it to absorb fully before applying moisturizer or serum. Use twice daily, morning and night, to maximize the benefits of this antiaging, skin-renewing leave-on.
Visible improvements in skin smoothness, brightness, and fine lines may appear within two weeks of twice-daily use. Continued use supports long-term skin regeneration, leaving skin softer, firmer, and more radiant over time.

what customers say

real feedback from real users

Tamlynn P

Johannesburg

Phyto Nature E² is hydration in a bottle, it leaves my tight skin feeling deeply hydrated.

Catherina C

Free State, South Africa

My one skin concern was loss of firmness and after the first week of use, I noticed firmer, softer and glowing skin, I used it after cleansing and toning just before moisturising. I can't wait to see the results after a month or three.

Patrick B

Cape Town, South Africa

After about 10 days of use, my skin felt noticeably softer and smoother. A useful addition to a skincare routine to help combat aging