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recommended for:
- mature or prematurely-aging skin
- fine lines and wrinkles
- Loss of firmness and elasticity
Daily exosome leave-on visibly smooths and supports skin regeneration. Formulated with next-gen exosomes and enzymes, this lightweight, silky leave-on helps reawaken skin’s natural surface renewal process, improving natural regeneration by 86%.*
Exfoliating enzymes help clear away dull surface cells, revealing smoother, brighter skin. A regenerative exosome blend acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles. In an independent clinical study, fine lines and wrinkles were visibly diminished in 2 weeks.*
*Versus untreated skin. Based on in vitro testing.
**Results at 2 weeks, based on a reduction in visible signs of skin aging in an independent clinical study with 32 subjects, 2 applications/day.
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What customers say
Real feedback from real users
Phyto Nature E² is hydration in a bottle, it leaves my tight skin feeling deeply hydrated.
Tamlynn P
Johannesburg
My one skin concern was loss of firmness and after the first week of use, I noticed firmer, softer and glowing skin, I used it after cleansing and toning just before moisturising. I can't wait to see the results after a month or three.
Catherina C
Free State
After about 10 days of use, my skin felt noticeably softer and smoother. A useful addition to a skincare routine to help combat aging
Patrick B
Cape Town
benefits
Accelerates skin's natural cellular renewal
Resurfaces to reveal brighter, smoother skin every day
how to use
Apply to clean skin. Allow to absorb, then follow with the rest of your skin care routine. Use twice daily.
ingredients
Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral. Dermalogica is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are complete, up-to-date and/or error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
FAQs
Who is this leave-on recommended for?
What are the key active ingredients?
What benefits does it provide?
What do exosomes do for skin?
What are exosomes in skincare?
What is the texture like?
How do I use this leave-on?
Can I layer it with other products?
Is it suitable for sensitive skin?
When can I expect to notice differences?

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i have started using the Phyto Nature E2 since January and i cannot believe the significant difference in my skin. I have used dermalogica for a few years and i have always said the Precleanse oil is my favourite that i cannot live without but i think it has some competition now. I use my E2 every day twice a day and the difference to the texture and tone of my skin has been amazing. I absolutely love this product!
My skin thanks me daily for this miracle in a bottle. I've noticed that my skin is smoother, softer, I have a beautiful glow. I'm now confident enough to go without makeup.
From the word go I could see a marked difference!